The singer told David Frost: ‘She certainly didn't break the group up, the group was breaking up.
Since the wildly popular group parted ways in the 1970s, many diehard fans have felt that John Lennon’s widow was responsible.
However, McCartney indicated that they should actually thank her for the more 'avant garde' side of Lennon’s material, as without her songs like Imagine would never have been written.
He revealed: ‘I don't think he would have done that without Yoko, so I don't think you can blame her for anything.
'When Yoko came along, part of her attraction was her avant garde side, her view of things, so she showed him another way to be, which was very attractive to him.'
He added that, one way or another, John was definitely going to leave the group.
The ageing pop star also said there were no hard feelings, explaining that in retrospect it was a good time for the group to split.
They left a 'neat body of work' behind, and the break-up therefore 'wasn't that bad a thing,' he explained.